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This paper proposes a scheme based on the use of unsupervised machine learning approach and a drift detection mechanism in order to perform an early fault diagnosis of simple and multiple stuck-opened/stuck-closed switches in multicellular converters. Only the data samples representing the normal operation conditions are used in order to be adapted to the case where no data is available about faulty behaviors. A health indicator measuring the dissimilarity between normal and current operation conditions is built in order to detect a drift