https://www.selleckchem.com/pr....oducts/CHR-2797(Tose
Osteoarthritis (OA) is a degenerative joint disease that seriously affects the quality of life of patients. Irisin has been reported to regulate bone metabolism via the cellular autocrine mechanism and play a protective role in rat OA. In the present study, a SW1353 chondrosarcoma cell line was treated with interleukin (IL)-1β and irisin. The present study evaluated cell viability, expression levels of collagen II (Col II) and matrix metalloproteinase-13 (MMP-13), and activity of the Wnt/β-catenin and NF-κB signaling pathwa
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