https://www.selleckchem.com/pr....oducts/vorapaxar.htm
The adjusted hazard ratio (aHR) of dementia for patients with UGID receiving gastric acid-suppressive agents compared with patients with UGID without gastric acid-suppressive agents was 1.470 (95% confidence interval [CI] 1.267-1.705, p 0.001). Both PPIs and H2RAs increase the risk of dementia (PPIs aHR 1.886 [95% CI 1.377-2.582], p 0.001; H2RAs aHR 1.357 [95% CI 1.098-1.678], p 0.01), with PPIs exhibiting significantly greater risk (aHR 1.456 [95% CI 1.022-2.075], p 0.05). Our results demonstrate an increased risk