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Acute appendicitis is the most common abdominal urgency around the world. Recent studies have investigated the efficacy of platelet distribution width (PDW) in the diagnosis of acute appendicitis. To determine if there is a correlation between PDW and the diagnosis of patients with acute appendicitis and to define their relation to the phases of appendicitis. A case-controlled study was conducted in two population groups with 41 patients older than 18 years of age diagnosed with acute appendicitis (group I) and 41 healthy patients (gro