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Conclusions OCN and OPN may serve as potential biomarkers for PD. The inflammation response may be involved in the cross-talk between the two factors and PD.Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, psychiatric symptoms and behavioral disorders, resulting in disability, and loss of self-sufficiency. Objective To establish an AD-like mice model, investigate the behavioral performance, and explore the potential mechanism. Methods Streptozotocin (STZ, 3 mg/kg) was micr
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