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Retrieved researches will be separately evaluated by two authors and any discrepancies are settled by consensus or with a 3rd reviewer. Reviewers will draw out the data and measure the risk of bias associated with the chosen studies. If at all possible, information is going to be combined in a quantitative meta-analysis following recommendations supplied by Cochrane Handbook for organized Reviews of Interventions. We're going to examine cumulative evidence utilising the Grading of Reco

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