https://www.selleckchem.com/pr....oducts/pi4kiiibeta-i
Moreover, IGFBP-3 depletion in OSCC cells reduced phosphorylation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), which is required for DNA double-strand break repair during non-homologous end joining. These findings indicate that IGFBP-3 may have a significant role in regulating DNA repair and is be a potential biomarker for predicting clinical response to radiotherapy and prognosis in OSCC.Metabolic homeostasis is differently regulated in males and females. Little is known about the mitochondrial Sirtuin 3
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