https://www.selleckchem.com/pr....oducts/Raltitrexed.h
BACKGROUND Filamin A is the most widely expressed isoform of filamin in mammalian tissues. It can be hydrolyzed by Calpain, producing a 90-kDa carboxyl-terminal fragment (ABP9. Calpeptin is a chemical inhibitor of Calpain, which can inhibit this effect. #link# It has been shown that ABP90 acts as a transcription factor which is involved in mediating cell signaling. However, the significance of ABP90 and its clinical signature with underlying mechanisms have not been well studied in glioblastoma multiforme (GBM). METHODS ABP90 prot
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