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Importance Peptidoglycan is a key element of the bacterial cell wall to maintain the cell shape and protect the cell from bursting. Peptidoglycan degradation, by peptidoglycan hydrolysis and autolysins, occurs during growth and cell division. Since peptidoglycan hydrolases are important for virulence, envelope integrity and regulation of cell division, it is valuable to investigate their function and regulation. Notably, PcsB-like proteins such as Usp45 have been proposed as new targets for antimicrobial drugs and could also be target fo
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