https://www.selleckchem.com/pr....oducts/crt-0105446.h
Introduction Some evidence demonstrates endogenous inhibitory pathways of pain involved in the interphase (phase between early and later phase) of the formalin test. We previously showed that swimming stress modulates the pain-related behaviors during the interphase of the formalin test. In this study, we evaluated the role of the endogenous opioid system in modulating nociceptive responses of the formalin test. Methods Swim stress was performed in different heights of water (5, 25, 50 cm) in a swimming tank. The mean nociceptive sc
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