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Pharmacokinetics (PK) are severely modified in pregnant women due to alterations in amount of distribution (Vd) and/or medicine clearance (CL), affecting target attainment of antibiotics in expectant mothers. This review is part of a series that reviews literature on the description of PK and target attainment of antibiotics in pregnant women with specific consider penicillins. a systematic literature search was performed in PubMed. Articles had been labe