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How Does Medication For ADHD Work? Stimulants boost the levels of norepinephrine and dopamine in your brain, helping improve concentration and impulse control. They are available in both immediate-release (short acting) and extended release tablets that can be taken daily in the morning. Nonstimulant medications take longer to work but can also improve the ability to control impulses and attention. Atomoxetine (Strattera) and guanfacine (Viloxazine) are in the class of antidepressants