https://encorafenibinhibitor.c....om/a-planned-out-eva
DSBs may be repaired by either non-homologous end joining (NHEJ) or homologous recombination (hour). The choice between those two pathways depends on which proteins bind into the DSB ends and exactly how their particular action is managed. NHEJ initiates with the binding associated with Ku complex into the DNA ends, while HR is initiated by the nucleolytic degradation associated with the 5'-ended DNA strands, which requires several DNA nucleases/helicases and yields single-stranded DNA overh
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