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M192I, A103VI, and G74A substitutions were frequently noted in the ribosomal proteins L4 or L22. Further, we identified a considerable proportion (90%) of erythromycin-resistant isolates carrying virulence factor genes flaA, cadF, ceuE, and VirB. The prudent use of antimicrobials and regular microbiological investigation in food animals will be vital in limiting the public health hazards of C. coli in Korea.Numerous viruses hijack cellular protein trafficking pathways to mediate cell entry or to rearrange membrane struc