https://www.selleckchem.com/pr....oducts/cirtuvivint.h
the incidence of serious infections was generally higher in patients aged ≥ 65 years regardless of treatment. Conclusions Apart from ACPA status, there were no consistent signals indicating differential effects of sarilumab in any of the subpopulations assessed. Sarilumab demonstrated consistent efficacy and safety across a wide range of patients with RA. Trial registration ClinicalTrials.gov NCT01061736, registered on February 03, 2010; ClinicalTrials.gov NCT01709578, registered on October 18, 2012; ClinicalTrials.gov NCT02332590,