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These faculties tend to be known as the "stemness" properties. Tumor microenvironment contributes to CSC success, purpose, and continuing to be all of them in an undifferentiated condition. CSCs can form malignant tumors with heterogeneous phenotypes mediated by the tumor microenvironment. Consequently, the crosstalk between CSCs and tumor microenvironment can modulate tumor heterogeneity. CSCs perform a vital role in many biological processes, epithelial-mesenchymal change (EMT), autoph
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