https://hedgehogsignaling.com/....chances-pertaining-t
We established the potent anti-tumor abilities of your lead candidate MTP10-HDL in a B16F10 mouse melanoma design. These anti-tumor effects derive from trained immunity-induced myelopoiesis due to epigenetic rewiring of multipotent progenitors into the bone marrow, which overcomes the immunosuppressive tumor microenvironment. Also, MTP10-HDL nanotherapy potentiates checkpoint inhibition in this melanoma model refractory to anti-PD-1 and anti-CTLA-4 therapy. Finally, we determined MTP
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