https://www.selleckchem.com/pr....oducts/cfi-402257.ht
ImportanceBiological secretions allow viruses to spread between individuals. Each type of secretion has a unique composition of proteins, salts and sugars, which can affect infectivity potential of the virus and inhibition of this process. Here we describe HIV-1 infection and inhibition in whole human semen and a synthetic simulant we formulated. We discovered that the sugar fructose in semen decreases the activity of a broad and potent class of antiviral agents that target mannose sugars on the envelope protein of HIV-1. This effect
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