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The consistence of the behavioral, ERP and effective connectivity results suggested that under the negative emotion condition, the top-down attention modulation between the frontoparietal area and posterior area could promote the most relevant information storage during WM maintenance. © 2020 IOP Publishing Ltd.Biological cells are complex environments that are densely packed with macromolecules and subdivided by membranes, both of which affect the rates of chemical reactions. It is well known that crowding reduces the volume available to

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