https://www.selleckchem.com/pr....oducts/lazertinib-yh
Higher levels of VEGF (p less then 0.01) and OPN (p less then 0.01) immunostaining in the epiphysis, the greater formation of osteoid tissue (p less then 0.01 on Day 7; p less then 0.05 on Day 14), and higher levels of PAS staining (p less then 0.01 on Day 7) were observed in the sildenafil-treated group. The present study demonstrated that sildenafil optimized bone tissue regeneration by increasing VEGF signaling and OPN expression, with increased bone formation (osteoid and carbohydrate macromolecule depo