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To report two unusual cases of optic disc hemorrhage occurring following pharmacologic mydriasis. A 78-year old woman and 60-year old man with primary open angle glaucoma developed optic disc hemorrhages shortly after pupillary dilation. Cycloplegia may cause subtle shifts in vitreous and lamina cribrosa position that may result in the formation of optic disc hemorrhages in susceptible glaucomatous eyes. Cycloplegia may cause subtle shifts in vitreous and lamina cribrosa position that may result in the formation of optic disc hemorrhages
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