https://www.selleckchem.com/pr....oducts/Cyclopamine.h
greater AUC (612.7 [17.42] ng.h/mL) and higher C (262.4 [38.86] ng/mL) compared with Sinemet CR AUC 354.7 (98.09) ng.h/mL and C 95.5 (20.87) ng/mL. However, Sinemet CR had a much longer half-life (6.1 [2.58] hours) compared with levodopa/carbidopa microparticles (2.0 [0.31] hours). Findings from this study suggest that chitosan-coated hydroxypropylmethyl cellulose microparticles of levodopa/carbidopa may give relatively high levels of levodopa in circulation. ( 2020; 81XXX-XXX)© 2020 Elsevier HS Journals, Inc. Findings from this stu