https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Strikingly, murine hepatocytes cleared HDV within 21days both in immunocompetent hNTCP mice and in immunodeficient USB mice xenografted with murine hepatocytes. In contrast, HDV infection remained stable for at least 42days in human hepatocytes. Intrinsic innate responses were not enhanced in any of the HDV mono-infected cells and livers. These findings suggest that in addition to NTCP, further species-specific factors limit HDV infection efficacy and persistence in murine hepatocytes. Identifying such species barriers may
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