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12% were underestimated and the Japan Esophageal Society classification (JES) was better than Inoue (Accuracy 75.48% VS 58.67%, P less then 0.05). For ≥ SM2, 38.86% were underdiagnosed and the diagnostic accuracy of Arima classification was significantly higher than the other two (P less then 0.05). Our study showed that the new criteria had higher diagnostic sensitivity than the widely used classification (JES) for differentiating ≥ SM2 staging cancer from EP-SM1 (0.77 VS 0.50, P less then 0.05). CONCLUSIONS IPCL was valuable for