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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression When a person suffers from both ADHD and anxiety or depression, treating the first condition can often improve the second. Mental health professionals typically prescribe antidepressants or a stimulant for depression in addition to an ADHD medication. Wellbutrin (bupropion) and Effexor (venlafaxine) are the most commonly used antidepressants that are prescribed "off-label" for ADHD. These medications increase levels of the neurotransmitters norepinephrine as wel
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