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l for nephrologists caring for kidney transplant recipients. Hyperkalemia is a common electrolyte abnormality of chronic kidney disease and heart failure associated with increased mortality and morbidity. We aimed to assess the long-term economic burden of hyperkalemia. Observational cohort study using a Japanese nationwide hospital claims database (April 1, 2008, to September 30, 2018). Patients 18 years or older with at least 1 serum potassium value (N= 1,208,894). Hyperkalemia defined with the presence of at least 2 serum potassium va