https://www.selleckchem.com/pr....oducts/gsk923295.htm
All these abnormalities are typical features of early vascular aging described in adults with PH. However, as these early vascular changes in hypertensive children are closely associated with features of accelerated biological development and neuro-immuno-metabolic abnormalities observed in older subjects, it seems that PH in childhood is not only an early vascular aging event, but also an early biological maturation phenomenon.Recent randomized sham-controlled trials have demonstrated significant blood pressure reductions following r