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ADHD Medications For Adults Stimulants can help regulate the levels of chemical messengers which control the brain's attention. They are first-line medications to treat ADHD. They aren't thought to be habit-forming, but they can trigger side effects, such as headaches and sleep problems. To decrease impulsivity or hyperactivity the doctor could prescribe guanfacine with the brand names Tenex or Intuniv (Catapres). These drugs have a longer duration of action than stimulant