https://zileutoninhibitor.com/....pattern-mixture-prod
ATAMs are gene-modified CD3ζ with all the intracellular domain of 4-1BB placed in the exact middle of CD3ζ. NY-ESO-1 TCR-T cells transduced with an ATAM with two isolated virus vectors demonstrated superior proliferation upon antigen stimulation. To advance develop medically applicable ATAM-transduced TCR-T cells, we attemptedto make an individual virus vector to transduce the TCR and ATAM simultaneously. Because we didn't observe improved expansion capacity upon stimu
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