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In contrast, the levels of related kinases, phosphatases, and transfer proteins were unaltered in the Npc1-null mouse model as observed by Western blot analysis. Our discovery of phosphoinositide lipid biomarkers for NPC1 opens new perspectives on the pathophysiology underlying this fatal neurodegenerative disease. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.Information about the clinical presentation and course of COVID-19 is rapidly evolving. Data are emerging from retrospective clinical s
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