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How Does ADHD Medication Work? When one neuron transmits signals to another, it uses neurotransmitters, which are chemicals that act as. They need to cross a tiny gap called a synapse. Certain ADHD medications boost the effectiveness of these messages. They can either aid in the release of neurotransmitters faster or slow the Reuptake (called Reuptake inhibitors). Doctors place patients with ADHD with a low dose of medication and then observe their reactions. They adjust the dosage over time to find the "sweet place" -the lowest dosage that shows noticeable impro
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