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ay help elucidate the potential mechanism and identify a potential treatment through using BBR for PCOS-mediated ASD. Copyright © 2020 Xiang, Lu, Wei, Cai, Wang, Liang, Xu, Wang, Liu, Wang, Liang, Li and Yao.The intrinsic nervous system of the gut interacts with the gut-associated lymphoid tissue (GALT) via bidirectional neuroimmune interactions. The caecum is an understudied region of the gastrointestinal (GI) tract that houses a large supply of microbes and is involved in generating immune responses. The caecal patch is a lymphoid ag