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Our study suggests that ELII is a promising approach supporting fast temporal query, an important mode of cohort development for Covid-19 studies. To analyse the strains collected during a 1-year survey of ceftazidime-avibactam-resistant KPC-producing Klebsiella pneumoniae, in order to investigate the molecular mechanisms potentially responsible for their resistant phenotype. Clinical KPC-producing K.pneumoniae isolates were collected from 31 patients in six different hospitals in Rome. For eight of the patients, an additional strain gr