https://www.selleckchem.com/pr....oducts/GSK1059615.ht
Amphiregulin (Areg), a glycoprotein from the epidermal growth factor receptor (EGFR) ligand family, has a well-documented protective role against tissue injury; however, its effects on immune-mediated liver injury are still unclear. Here, we used a concanavalin A (ConA)-induced acute liver hepatitis model to explore the effects of Areg on immune-mediated acute liver injury. Some C57BL/6 mice were administered ConA at a dose of 20 mg/kg (model mice), and some received 5µg of Areg (treated mice). Then, their survival rates over 36 h we
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