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78, p = 0.046) and change in surgical strategy (OR = 5.30, p = 0.023). Functional class III-IV (OR = 6.98, p 0.001), renal failure (OR = 5.75, p = 0.001), CIED infection (OR = 13.30, p 0.001), number of procedures performed (OR = 77.32, p 0.001) and major intraoperative complications (OR = 38.84, p 0.001) were predictors of 30-day mortality. The results of this study, which is the largest prospective registry of consecutive TLE procedures in Latin America, confirm the safety and effectiveness of this procedure

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