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Using 39/390/1000 as the cut-off values for preoperative serum CA19-9, significant capability of OS stratification was found in the total cohort (p0.001, MST=29.7/19.1/15.2/12.1 months) and patients with TBIL 102.6μmol/L (p0.001, MST=32.2/19.6/15.0/11.2 months). However, in the subgroup of TBIL≥102.6μmol/L, this classification method was replaced by the combined scoring of CA19-9/AST and CA19-9/γ-GGT. As an independent predictor of overall survival of PDAC patients, preoperative serum CA19-9 is defective in survival stratifi
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