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The Most Effective ADHD Medication For Adults Stimulants are the first choice of medication for adults with ADHD. They assist in adjusting the levels of two chemical messengers within the brain that regulate the ability to pay attention. The most effective treatment for adhd for adults is Strattera (atomoxetine). It is available in a capsule that can either be taken with food or without. It works well for most people. It lasts longer than stimulants with a shorter duration of action like amphetamine or methylphenidate. 1. Strattera Stratter
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