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ADHD Medications - Stimulant Or Non Stimulant? Stimulant medications are the first-choice ADHD treatment, because they are the most researched and have a rapid-acting effect. However, they're not for everyone. These drugs increase the communication between nerves and the regions of the brain to lessen symptoms of ADHD. They can also have negative side effects, such as an appetite loss and changes in heart rate or blood pressure. Stimulants Stimula
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