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Multivariable analysis showed a subordinate role of intraocular pressure predictive factor for impaired retinal blood flow compared with plasma ET-1 level in glaucoma. Peripheral ET-1 level serves as risk factor for detection of ocular blood flow changes in the optic nerve head region of glaucomatous eyes.Optical coherence tomography (OCT) is a three-dimensional optical imaging technique, frequently (but not exclusively) used for retinal imaging, that was first reported in the early 1990s. Since this time the technological development o