https://www.selleckchem.com/pr....oducts/pf-06700841.h
The immediate postexercise/physical activity period is critical for sickle cell trait (SCT) carriers and disease (SCD) patients. Exercise-related blood acidosis is known to trigger the cascade of HbS deoxygenation and polymerization, leading to red blood cell sickling and subsequent complications. Unfortunately, two facts worsen exercise-related blood acidosis during the initial postexercise period First, blood lactate and H+ concentrations continue to increase for several minutes after exercise completion, exacerbating blood acidos
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