https://www.selleckchem.com/pr....oducts/spop-i-6lc.ht
This reduces the concentration of free metal ion available for the catalytic reaction, and thus further inhibits the enzymatic activity. The combination of these two effects accounts for the inhibition of the enzyme at high concentrations of ATP. Taken together, our structural and biochemical data reveal the molecular mechanism for the dual regulatory roles of ATP on the αγ heterodimer of human NAD-IDH.Resistance to antimalarial drugs is currently a growing public health problem, resulting in more cases with treatment failure. Althou
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