https://www.selleckchem.com/pr....oducts/epz020411.htm
In cells, DNA-binding deficiency of UAF1 increased DNA damage sensitivity and impaired HR efficiency, suggesting that UAF1 and RAD51AP1 have coordinated roles in DNA binding during HR and DNA damage repair. Our findings show that, even though UAF1's DNA-binding activity is redundant with that of RAD51AP1 in FANCD2 deubiquitination, it is required for efficient HR-mediated chromosome damage repair. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.OBJECTIVE To evaluate the effect of aerobic exe
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