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Nitrite stress is a major environmental factor that limits aquatic animal growth, reproduction and survival. Even so, some shrimp can withstand somewhat high concentrations of nitrite environment as our previous studies indicated. Therefore, we hypothesized that these shrimps might have specific adaptive strategies to adapt to high concentrations of nitrite environment. To identify the genes and pathways involved in the regulation of nitrite tolerance, we performed comparative transcriptomic analysis in the Litopenaeus vannamei nitrite
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