https://nsc27640inhibitor.com/....heterochiral-tetrape
ConBr increased p38MAPK and JNK and decreased ERK1/2 and Akt phosphorylation. More over, ConBr inhibited mTORC1 phosphorylation related to buildup of autophagic markers, such as acid vacuoles and LC3 cleavage. Inhibition of early steps of autophagy with 3-methyl-adenine (3-MA) partially safeguarded whereas the later autophagy inhibitor Chloroquine (CQ) had no protective impact upon ConBr cytotoxicity. ConBr additionally augmented caspase-3 activation wi
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