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The CRISPR/dCasRx-SINEB2 technology was created in this research by coupling the sgRNA of a catalytically inactive Type VI-D Cas13 chemical (CasRx) to an integrated SINEB2 domain of uchl1 lncRNA that promotes the translation of targeted mRNA. It has been demonstrated to be effective and adaptable in selectively enhancing the expression of many different exogenous and endogenous proteins with a variety of features with minimal off-target impacts. dCasRx-SINEB2 is the sole CRISP
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