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The Most Effective ADHD Medication For Adults Most ADHD medications are classified into two categories: stimulants and nonstimulants. stimulants like methylphenidate and amphetamines boost brain activity areas that control attention and behavior. Non-stimulants, like atomoxetine (Strattera), guanfacine (Intuniv) and clonidine (Kapvay) perform slower than stimulants but help improve focus, concentration and impulsivity. They also appear to decrease anxiety, which is often comorbid
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