https://www.selleckchem.com/pr....oducts/caerulein.htm
Copyright © 2020 Cold Spring Harbor Laboratory Press; all rights reserved.Upstream Activation Factor (UAF) is a multifunctional transcription factor in Saccharomyces cerevisiae that plays dual roles in activating RNA Polymerase I (Pol I) transcription and repression of Pol II. For Pol I, UAF binds to a specific upstream element in the rDNA promoter and interacts with two other Pol I initiation factors, the TATA-Binding Protein (TBP) and Core Factor (CF). We used an integrated combination of chemical crosslinking mass spectrometry (CXM
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