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We give attention to aesthetic acuity, comparison susceptibility, shade vision, artistic field, and dark adaptation and their use to understand the pathophysiology of diabetic retinopathy and as prospective endpoints for clinical trials.A series of novel pyrrolopyrimidine urea derivatives had been synthesized and assessed with their anticancer task against colon cancer cell lines. Compounds revealed the remarkable cytotoxic task on HCT-116 wt cell range. The absolute most poten

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