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Finding the Best Medication For ADHD Stimulants are the most frequently prescribed drugs for ADHD. Amphetamines and methylphenidates are among the most commonly prescribed stimulants. Short-acting stimulants are effective within less than a minute and should be taken multiple times per day. Long-acting stimulants last for up to 16 hour and are taken once a day. Your doctor might prescribe antidepressants or other kinds of medication "off-label" to treat ADHD symptoms. These are approved medications f
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