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43, 95%CI 0.20-0.92, = 0.03), whereas no significant differences were identified in the female subjects (OR = 1.07, 95%CI 0.52-2.20, = 0.85). The rs2228557, T allele was associated with KC (OR = 0.69, 95% CI 0.50-0.97, = 0.035). In the rs2228557 variant, T allele acts as a protective factor from the disease and decreases the risk of KC compared with the C allele. Also, in our investigation about rs4898, we found that TY genotype or T allele decreased the risk of KC compared with the C allele in males and was a protective factor for KC i
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